Abstract:

Objective To compare the efficacy and safety of two approaches：laparoscopic cholecystectomy （LC）+ laparoscopiccommon bile duct exploration（LCBDE）single⁃stage bile duct suture andendoscopic retrograde cholangiopancreatography（ERCP）+ LC. Methods A total of 275 patients with cholecystolithiasis complicated with choledocholithiasis admitted to our hospital from September 2018 to September 2020 were selected and divided into control and observation groups in the study. LC + ERCP was performed in the control group，and LC + LCBDE was performed in the observation group. The clinical efficacy and safety of the two groups were compared. Results The amount of intraoperative bleeding in the control group was lower than that in the observation group（P < 0.001）. As compared with the observation group，the hospitalization time was significantly longer，the hospitalization cost significantly larger and the rates of stone residue and abnormality of liver function were significantly higherin the control group（P < 0.05）. Logistic regression analysis showed that the factors affecting the prognosis were postopera⁃ tive blood loss，length of stay，cost and abnormal liver function indexes（P < 0.05）. The lithotomy rate of the observa⁃ tion group was significantly higher than that of the control group（P < 0.05）. There was no significant difference in the incidence of complications between the two groups（P > 0.05）. Conclusion LC + LCBDE primary bile duct suture has higher efficacy and safety，which is beneficial for the improvement of clinical liver function indexes， reduction of hospital stay and lowering of cost. It is of high value clinically，worthy of promotion and application.

Key words:

LC, LCBDE, bile duct primary suture, ERCP + LC, efficacy, safety